Notational Velocity - Modeless, mouseless Mac OS X note-taking application

Notational Velocity is a modeless, mouseless Mac OS X note-taking application. The window was designed for keyboard input above all else, and thus has no buttons. There is no manual "saving" in Notational Velocity; all modifications take effect immediately. Synchronize natively with Simplenote, or via files in Dropbox with PlainText, Elements, iA Writer, and other iOS apps. All content is compressed and encrypted (enabled optionally) before it is recorded to disk.